Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Histone H4K8ac (Acetyl H4K8) Polyclonal Antibody. Unconjugated. Raised in: Rabbit
Human, Mouse, Rat, Monkey
Synthesized peptide derived from human Histone H4 around the acetylation site of K8.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
H4K8ac antibody; H4K8a antibody;H4; H4/n; H4F2; H4FN; FO108; HIST2H4
WB, IHC, IF, ELISA, ChIP; Recommended dilution: WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000