Histone H4K8ac (Acetyl H4K8) Polyclonal Antibody

Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Description
Histone H4K8ac (Acetyl H4K8) Polyclonal Antibody. Unconjugated. Raised in: Rabbit

Purification
Affinity purified

Specificity 
Human, Mouse, Rat, Monkey

Isotype
IgG

Immunogen 
Synthesized peptide derived from human Histone H4 around the acetylation site of K8.

Formulation 
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
H4K8ac antibody; H4K8a antibody;H4; H4/n; H4F2; H4FN; FO108; HIST2H4

Application 
WB, IHC, IF, ELISA; Recommended dilution: WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:5000