Histone H3K4me3 Trimethyl Peptide, Biotinylated

Description
Synthesized trimethyl histone H3-K4 peptide derived from residues within 1-100 of human histone H3, biotin conjugated.

Purity
>90% by HPLC analysis

Concentration
0.27 mg/ml (100 µM)

Formulation
PBS buffer

Storage
-20°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.

Application
Enzyme activity
Histone affinity precipitation assay

Handling Recommendations
For maximum recovery of the products, centrifuge the vial prior to opening the cap.

Usage
Research use only.

1. Xin X et. al. (June 2024). Temperature-dependent jumonji demethylase modulates flowering time by targeting H3K36me2/3 in Brassica rapa. Nat Commun. 15(1):5470.
2. Zhao X et. al. (January 2024). Temporally-coordinated bivalent histone modifications of BCG1 enable fungal invasion and immune evasion. Nat Commun. 15(1):231.
3. Xu Y et. al. (September 2014). Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes. Nucleic Acids Res.