SIRT3 is a member of the sirtuin (silent mating type information regulation 2 homolog) family of proteins which are characterized by a sirtuin core domain and are grouped into 4 class types. Sirtuins share NAD dependency for their enzymatic activity, but some show NAD-dependent deacetylase activity, while others exhibit ADP ribosyltransferase activity or both. Sirtuins may act to influence a wide range of cellular processes such as aging, transcription, apoptosis, inflammation and stress resistance. Seven members make up the family of sirtuins in mammals (SirT1-T7). SIRT3 is a Class I sirtuin.
SIRT3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recombinant Protein of Human SIRT3
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.
WB, IHC; Recommended dilution: WB 1:500 - 1:2000, IHC 1:100 - 1:200