SARS-CoV-2 N Protein Monoclonal Antibody

Background
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Description
SARS-CoV-2 N Protein Monoclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide,pH7.3.

Specificity
2019-nCoV

Isotype
IgG

Uniprot ID
P59595

Purification
Affinity Purification

Immunogen
Recombinant fusion protein of SARS-COV-2 Nucleoprotein.

Storage
Shipped at 4°C. Store at 4℃. Avoid freeze / thaw cycles.

Alternative Names
Anti-coronavirus NP Antibody, Anti-coronavirus Nucleocapsid Antibody, Anti-coronavirus Nucleoprotein Antibody, Anti-cov np Antibody, Anti-ncov NP Antibody, Anti-novel coronavirus NP Antibody, Anti-novel coronavirus Nucleocapsid Antibody, Anti-novel coronavirus Nucleoprotein Antibody, Anti-NP Antibody, Anti-Nucleocapsid Antibody, Anti-Nucleoprotein Antibody

Application
WB, ELISA, FCM, IHC, IF, IP; Recommended dilution: WB, 1:1000 - 1:5000; ELISA, 1:1000 - 1:5000; FCM, 1:50 - 1:200; IHC, 1:50 - 1:200; IF, 1:50 - 1:200; IP, 1:50 - 1:200