BackgroundProbably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
DescriptionNCDN Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman, Rat
IsotypeIgG
Uniprot IDQ9UBB6
Purification>95%, Protein G purified
ImmunogenRecombinant Human Neurochondrin protein (403-516AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesNeurochondrin, NCDN, KIAA0607
ApplicationELISA, WB, IHC, IF; Recommended dilution: WB: 1:500-1:5000, IHC: 1:500-1:1000, IF: 1:50-1:200