BackgroundThis gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
DescriptionLDHB Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP07195
PurificationAffinity Purified
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human LDHB (NP_002291.1).
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesLDHB; HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5
ApplicationWB, IHC; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200