BackgroundThis gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
DescriptionHMGB1 Recombinant Monoclonal Antibody [1A1]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP09429
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human HMGB1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesHigh mobility group protein B1 (High mobility group protein 1) (HMG-1), HMGB1, HMG1
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200