Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
HIST1H2AG (Ab-29) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
Peptide sequence around site of Arg (29) derived from Human Histone H2A type 1
Shipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Histone H2A type 1, H2A.1, Histone H2A/p, HIST1H2AG, H2AFP, AND, HIST1H2AI, H2AFC, AND, HIST1H2AK, H2AFD, AND, HIST1H2AL, H2AFI, AND, HIST1H2AM, H2AFN
ELISA, WB, IHC, IF; Recommended dilution: WB:1:200-1:2000, IHC:1:10-1:100, IF:1:1