BackgroundAs an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).
DescriptionGBP5 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDQ96PP8
PurificationProtein G purified
ImmunogenRecombinant Human Guanylate-binding protein 5 protein (321-500AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesGuanylate-binding protein 5 (EC:3.6.5.-2 Publications, GBP5, UNQ2427/PRO4987, GBP-TA antigen, GTP-binding protein 5, GBP-5, Guanine nucleotide-binding protein 5
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200