BackgroundAs an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).
DescriptionGBP5 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ96PP8
Purification>95%, Protein G purified
ImmunogenRecombinant Human Guanylate-binding protein 5 protein (321-500AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesGuanylate-binding protein 5 (EC:3.6.5.-2 Publications, GBP5, UNQ2427/PRO4987, GBP-TA antigen, GTP-binding protein 5, GBP-5, Guanine nucleotide-binding protein 5
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500