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EXO1 Polyclonal Antibody

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Western blot
All lanes: EXO1 Polyclonal Antibody at 10ug/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Lane 3: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 95, 90 kDa
Observed band size: 94 kDa
Immunohistochemistry of paraffin-embedded human brain tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human stomach tissue at dilution of 1:100
Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A62518-02020 µg $99.00 
A62518-05050 µg $256.00 
A62518-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

Description
EXO1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q9UQ84

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Exonuclease 1 protein (301-600AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Exonuclease 1, hExo1, Exonuclease I, hExoI, EXO1, EXOI, HEX1

Application
ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

User Guide & MSDS

[User Guide]*
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