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EXO1 Polyclonal Antibody, HRP Conjugated

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Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A62519-05050 µg $256.00 
A62519-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

Description
EXO1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q9UQ84

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Exonuclease 1 protein (301-600AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Exonuclease 1, hExo1, Exonuclease I, hExoI, EXO1, EXOI, HEX1

Application
ELISA

User Guide & MSDS

[User Guide]*
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