DNA Methylation Analysis Toolbox

When it comes to DNA methylation, you have several tools at your fingertips from EpiGentek to help detect and measure methylation or activity levels. Whether you want to look at global methylation levels or explore gene-specific methylation sites, we make it easy, affordable, and convenient with our widely-cited assay kits and high-quality antibodies. Best of all, each kit and antibody comes standard with our 100% 6-month application guarantee, ensuring your new DNA methylation tools are the right ones for the job in your lab.

Choose The DNA Methylation Tools That Work Best For Your Research Project

Quickly Measure Global DNA Methylation

Accurately Assess DNMT & Demethylase Activity Levels

Cut Down On Your MeDIP Protocol Time

Drill Down To Gene-Specific Methylated Sites With Bisulfite Conversion

Global DNA Methylation Kits

Quickly Measure Global DNA Methylation

A few notable benefits include:

• Rapid streamlined procedures as fast as 2 hours
• Detection from as low as 0.05%/0.01% of methylated/hydroxymethylated DNA
• No cross-reactivity to unmethylated cytosine or other modified cytosines

Catalog #	Name	Description
P-1030	MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit	For quantitation of global DNA methylation via a one-step ELISA method in just 2 hours
P-1032	MethylFlash Global DNA Hydroxymethylation (5-hmC) ELISA Easy Kit	For quantitation of global DNA hydroxymethylation via a one-step ELISA method
P-1041	MethylFlash 5-Formylcytosine (5-fC) DNA Quantification Kit	For absorbance-based quantitation of global 5fC levels in an ELISA-like format

DNA Methyltransferase & Demethylase Kits

Accurately Assess DNMT & Demethylase Activity Levels

A few notable benefits include:

• Rapid streamlined procedures as fast as 2 hours
• Detection as low as 0.2 ng of purified enzymes
• Manual or high throughput capabilities

Catalog #	Name	Description
P-3139	EpiQuik DNMT Activity/Inhibition ELISA Easy Kit	For measuring DNA methyltransferase activity or inhibition in just 2 hours
P-3086	Epigenase 5mC-Hydroxylase TET Activity/Inhibition Assay Kit	For measuring enzymatic activity or inhibition levels of TET enzyme
P-3094	Epigenase Thymine DNA Glycosylase (TDG) Activity/Inhibition Assay Kit	For measuring enzymatic activity or inhibition levels of TDG enzyme
P-3008	EpiQuik DNA Demethylase Activity/Inhibition Assay Ultra Kit	For measuring total DNA demethylase activity or inhibition using nuclear extracts from a broad range of species

Methylated DNA Immunoprecipitation (meDIP/hmeDIP) Kits

Cut Down On Your MeDIP Protocol Time

A few notable benefits include:

• Highly efficient enrichment of methylated DNA
• Compatible with all DNA amplification-based approaches
• Manual or high throughput capabilities

Catalog #	Name	Description
P-1015	Methylamp Methylated DNA Capture (MeDIP) Kit	For enrichment and capture of methylated DNA fragments for microarray, PCR, or NGS applications
P-1052	EpiQuik MeDIP Ultra Kit	For antibody-based capture of methylated DNA fragments for microarray, PCR, or NGS applications
P-2020	EpiQuik Tissue Methylated DNA Immunoprecipitation Kit	For enrichment and capture of methylated DNA from various mammalian tissues for microarray, PCR, or NGS applications
P-1038	EpiQuik Hydroxymethylated DNA Immunoprecipitation (hMeDIP) Kit	For antibody-based capture of hydroxymethylated DNA fragments for microarray, PCR, or NGS applications

DNA Bisulfite Conversion Kits

Drill Down To Gene-Specific Methylated Sites With Bisulfite Conversion

A few notable benefits include:

• Rapid streamlined procedures as fast as 30 minutes
• Completely converts unmethylated cytosine into uracil
• Directly modify DNA in cells or tissues

Catalog #	Name	Description
P-1026	BisulFlash DNA Modification Kit	For lightning-fast bisulfite treatment of DNA for methylation-specific PCR analysis in just 30 minutes
P-1001	Methylamp DNA Modification Kit	For robust, chemical-based bisulfite conversion of DNA for methylated cytosine analysis
P-1016	Methylamp Whole Cell Bisulfite Modification Kit	Directly carry out bisulfite conversion from cells, tissues, saliva, urine, or blood

To offer you a complete repertoire of tools to use during your DNA methylation studies, EpiGentek also provides the following for your convenience:

• Epigenetic Services for Reduced Representation Bisulfite Sequencing (RRBS)
• A variety of high-quality DNA Methylation Antibodies, including our anti-5mC and anti-5hmC - the same exceptional antibodies we use in our popular Methylflash Global DNA kits.