BackgroundHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher-order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21. 3.
DescriptionHistone H3K14ac (Acetyl H3K14) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP68431, Q71DI3, P84243
PurificationAffinity Purified
ImmunogenSynthesized peptide derived from Human Histone H3 around the acetylation site of K14.
StorageShipped at 4°C. Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.
Alternative NamesH3K14ac antibody; H3K14a antibody; H3t; H3.4; H3/g; H3FT
ApplicationWB, IF, ELISA; Recommended dilution: WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:5000