BackgroundThis gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
DescriptionVCAM1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP19320
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 300-400 of human VCAM1 (NP_001069.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesVCAM1; CD106; INCAM-100; vascular cell adhesion protein 1
ApplicationWB, IHC, IP; Recommended dilution: WB 1:1000 - 1:3000, IHC 1:50 - 1:200, IP 1:50 - 1:200