BackgroundThis is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
DescriptionTACR1 Recombinant Monoclonal Antibody [1E5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman, Mouse
IsotypeRabbit IgG
Uniprot IDP25103
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Neurokinin 1 Receptor
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesSubstance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1), TACR1, NK1R TAC1R
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:5000