BackgroundSET7, also known as SET 7/9, is a histone methyltransferase that specifically methylates histone H3 Lys4 (H3K4) and contains a SET domain. It acts on several non-histone as well as histone targets such as TAF10, histone H3, p53, and estrogen receptor alpha. SET7 is implicated in numerous human diseases due to its broad substrate specificity and researchers use SET7/9 as a model for investigating the mechanism of SET domain histone methyltransferases.
DescriptionSET07 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300.50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ8WTS6
PurificationProtein G purified
ImmunogenRecombinant Human Histone-lysine N-methyltransferase SETD7 protein (1-218AA)
StorageShipped at 4°C (Blue Ice). Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesHistone-lysine N-methyltransferase SETD7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9), SETD7, KIAA1717 KMT7 SET7 SET9
ApplicationWB, IHC, ELISA; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200