PVR Recombinant Monoclonal Antibody [19C12]

Background
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Description
PVR Recombinant Monoclonal Antibody [19C12]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity
Human

Isotype
Rabbit IgG

Uniprot ID
P15151

Purification
Affinity Chromatography

Immunogen
A synthesized peptide derived from Human PVR

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155), PVR, PVS

Application
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:50-1:200