OPRD1 Recombinant Monoclonal Antibody [7G7]

Background
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Description
OPRD1 Recombinant Monoclonal Antibody [7G7]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity
Human, Mouse

Isotype
Rabbit IgG

Uniprot ID
P41143

Purification
Affinity Chromatography

Immunogen
A synthesized peptide derived from human OPRD1

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
Delta-type opioid receptor (D-OR-1) (DOR-1), OPRD1, OPRD

Application
ELISA, WB; Recommended dilution: WB:1:500-1:5000