BackgroundThis gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
DescriptionOCRL Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ01968
PurificationAffinity Purified
ImmunogenRecombinant protein of human OCRL.
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesOCRL; INPP5F; LOCR; NPHL2; OCRL-1; OCRL1
ApplicationWB; Recommended dilution: WB 1:500 - 1:2000