BackgroundInvolved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.
DescriptionNSUN4 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ96CB9
Purification>95%, Protein G purified
ImmunogenRecombinant Human 5-methylcytosine rRNA methyltransferase NSUN4 protein (26-284AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names5-methylcytosine rRNA methyltransferase NSUN4 (EC:2.1.1.-), NSUN4, NOL1/NOP2/Sun domain family member 4
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-2000, IHC:1:20-1:200