BackgroundProtein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
DescriptionNEK11 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ8NG66
PurificationProtein G purified
ImmunogenRecombinant Human Serine/threonine-protein kinase Nek11 protein (245-482AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesSerine/threonine-protein kinase Nek11 (EC:2.7.11.1), NEK11, Never in mitosis A-related kinase 11, NimA-related protein kinase 11
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200