BackgroundThis gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
DescriptionMCL1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ07820
PurificationAffinity Purified
ImmunogenA synthetic peptide of human MCL1
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesMCL1; BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT; MCL1
ApplicationWB, IHC, IF; Recommended dilution: WB 1:500 - 1:1000, IHC 1:50 - 1:100, IF 1:50 - 1:100