Product Overview
Background
MBD5, or methyl-CpG binding domain protein 5, is a part of the methyl-CpG-binding domain (MBD) family, which also includes MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins. This protein contains a Pro-Trp-Trp-Pro motif (PWWP) domain as well as the MBD domain. The proteins of the PWWP domain play a role in cell division, cell growth, and cell differentiation. Evidence shows that diseases, such as mental retardation autosomal dominant type 1, can be caused by mutation to the MBD5 gene and some research indicates it may be involved in neurodevelopmental disorders and postnatal growth of mice.
Description
Rabbit polyclonal antibody to MBD5.
Concentration
Inquire
Formulation
Liquid in PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3..
Immunogen
Recombinant protein of human MBD5.
Uniprot ID
Q9P267
Specificity
Human, Mouse, Rat
Isotype
IgG
Purification
Affinity purified
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Alternative Names
MRD1
Application
WB (1:200 - 1:2000), ELISA (1:100 - 1:1000)
VCU0006