BackgroundMBD5, or methyl-CpG binding domain protein 5, is a part of the methyl-CpG-binding domain (MBD) family, which also includes MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins. This protein contains a Pro-Trp-Trp-Pro motif (PWWP) domain as well as the MBD domain. The proteins of the PWWP domain play a role in cell division, cell growth, and cell differentiation. Evidence shows that diseases, such as mental retardation autosomal dominant type 1, can be caused by mutation to the MBD5 gene and some research indicates it may be involved in neurodevelopmental disorders and postnatal growth of mice.
DescriptionMBD5 Polyclonal Antibody . Unconjugated. Raised in: Rabbit.
FormulationLiquid in PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ9P267
PurificationAffinity Purified
ImmunogenHuman MBD5
StorageShipped at 4°C. Aliquot store at -20°C . Avoid repeated freeze / thaw cycles.
Alternative NamesMRD1
ApplicationWB, ELISA
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