BackgroundCatalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues.
DescriptionHS2ST1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman, Rat
IsotypeIgG
Uniprot IDQ7LGA3
PurificationProtein G purified
ImmunogenRecombinant Human Heparan sulfate 2-O-sulfotransferase 1 protein (29-229AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesHeparan sulfate 2-O-sulfotransferase 1 (EC:2.8.2.-), 2-O-sulfotransferase, 2OST, HS2ST1, HS2ST, KIAA0448
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200