BackgroundSerine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization.
DescriptionHPN Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP05981
Purification>95%, Protein G purified
ImmunogenRecombinant Human Serine protease hepsin protein (294-413AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesSerine protease hepsin, Transmembrane protease serine 1, Serine protease hepsin non-catalytic chain, Serine protease hepsin catalytic chain, HPN, TMPRSS1
ApplicationELISA, WB, IHC, IF; Recommended dilution: WB: 1:500-1:5000, IHC: 1:200-1:500, IF: 1:50-1:200