Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Histone H2B Type 1-B Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
Human, Mouse, Rat
Protein G purified
Recombinant Human Histone H2B type 1-B protein (2-126AA)
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Histone H2B.1, Histone H2B.f, H2B/f, H2BFF, HIST1H2BB
ELISA, WB, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200