BackgroundCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
DescriptionHistone H2AB/E Monoclonal Antibody, clone RMC385C. Unconjugated. Raised in: Rabbit.
ConcentrationInquire
FormulationLiquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
Isotype IgG
Uniprot IDP04908
PurificationAffinity Purified
ImmunogenA synthesized peptide
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesHistone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, HIST1H2AB, H2AFM, AND, HIST1H2AE, H2AFA
ApplicationELISA, WB, IF; Recommended dilution: WB: 1:500-1:5000, IF: 1:30-1:200
VCU0006
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