BackgroundThis gene encodes a serine-threonine kinase from the glycogen synthase kinase subfamily. It negatively regulates glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptosis. It's linked to Parkinson's and Alzheimer's diseases due to defects in this gene.
DescriptionGSK3B Recombinant Monoclonal Antibody [9G11]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP49841
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human GSK3 beta
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesGlycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1), GSK3B
ApplicationELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
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