BackgroundIn the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion.
DescriptionGPI Recombinant Monoclonal Antibody [12A4]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP06744
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human GPI
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesGlucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (Sperm antigen 36) (SA-36), GPI
ApplicationELISA, WB, IHC, FC; Recommended dilution: WB:1:500-1:2000, IHC:1:50-1:200, FC:1:50-1:200
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