BackgroundInvolved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
DescriptionFGF19 Recombinant Monoclonal Antibody [11H3]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDO95750
PurificationAffinity-chromatography
ImmunogenA synthesized peptide derived from human FGF19
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesFibroblast growth factor 19 (FGF-19), FGF19
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:2000