BackgroundBinds to the Fc region of monomeric immunoglobulins gamma. Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids (By similarity). Possible role in transfer of immunoglobulin G from mother to fetus.
DescriptionFCGRT Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: Liquid in PBS containing 50% glycerol, 0.5% BSA* and 0.02% sodium azide
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDP55899
PurificationAntigen affinity purification
ImmunogenSynthesized peptide derived from human FCGRN
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesIgG Fc fragment receptor transporter alpha chain FCGRT FCRN
ApplicationELISA, WB; Recommended dilution: WB:1:1000-1:3000
Celebrate our 20th year anniversary with gifts on purchases above $300!
» Learn more
Cart (0)
