BackgroundThis gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.
DescriptionEBF3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9H4W6
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 400-500 of human EBF3 (NP_001005463.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesEBF3; COE3; EBF-3; HADDS; O/E-2; OE-2; early B-cell factor 3
ApplicationWB; Recommended dilution: WB 1:500 - 1:2000