DOT1L Recombinant Monoclonal Antibody [3B6]

Background
Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

Description
DOT1L Recombinant Monoclonal Antibody [3B6]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity
Human

Isotype
Rabbit IgG

Uniprot ID
Q8TEK3

Purification
Affinity Chromatography

Immunogen
A synthesized peptide derived from human KMT4 / Dot1L

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4), DOT1L, KIAA1814 KMT4

Application
ELISA, WB; Recommended dilution: WB:1:500-1:5000