BackgroundThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
DescriptionCHRM3 Recombinant Monoclonal Antibody [2D4]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP20309
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Muscarinic Acetylcholine Receptor M3
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesMuscarinic acetylcholine receptor M3, CHRM3
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200