BackgroundThe protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
DescriptionBRD4 Recombinant Monoclonal Antibody [1E5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDO60885
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Brd4
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesBromodomain-containing protein 4 (Protein HUNK1), BRD4, HUNK1
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
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