This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.
BMP7 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 132-431 of human BMP7 (NP_001710.1).
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
BMP7; OP-1; bone morphogenetic protein 7
WB; Recommended dilution: WB 1:500 - 1:2000