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ARHGEF7 Polyclonal Antibody

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Western blot
All lanes: ARHGEF7 Polyclonal Antibody at 2ug/ml
293T whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 91, 74, 85, 88, 83, 71 kDa
Observed band size: 90 kDa
Application: ELISA, IF, IP
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A53117-02020 µg $99.00 
A53117-05050 µg $256.00 
A53117-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions By similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Description
ARHGEF7 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q14155

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Rho guanine nucleotide exchange factor 7 protein (1-250AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB ORF Names: Nbla10314

Application
ELISA, IF, IP; Recommended dilution: IF:1:200-1:500, IP:1:200-1:2000

User Guide & MSDS

[User Guide]*
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