BackgroundSteroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
DescriptionAR Recombinant Monoclonal Antibody [5G7]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP10275
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Androgen Receptor
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesAndrogen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4), AR, DHTR NR3C4
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200