ACE2 Monoclonal Antibody

Background
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Description
ACE2 Monoclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
Q9BYF1

Purification
Affinity Purified

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-740 of human ACE2 (NP_068576.1).

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Alternative Names
ACE2, ACEH, angiotensin I converting enzyme 2, ACE2, angiotensin I converting enzyme 2, angiotensin-converting enzyme 2; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme homolog; metalloprotease MPROT15; peptidyl-dipeptidase A

Application
WB, IHC-P, IF/ICC, ELISA; Recommended Dilutions: WB 1:100 - 1:500, IHC-P 1:50 - 1:200, IF/ICC 1:50 - 1:200