BackgroundE3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
DescriptionTRIM38 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDO00635
PurificationProtein G purified
ImmunogenRecombinant Human E3 ubiquitin-protein ligase TRIM38 protein (45-259AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesE3 ubiquitin-protein ligase TRIM38 (EC:6.3.2.-), TRIM38, RNF15, RORET, RING finger protein 15, Tripartite motif-containing protein 38, Zinc finger protein RoRet
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:2000