BackgroundComponent of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
DescriptionSTAG2 Recombinant Monoclonal Antibody [3H4]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ8N3U4
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human SA2
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesCohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2), STAG2, SA2
ApplicationELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200
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