BackgroundSIRT5 (sirtuin 5) is a protein coding gene that is a member of sirtuin family of proteins which are homologs to the yeast Sir2 protein. Sirtuns are involved in a variety of cellular functions including gene silencing, histone deacetylation, chromosomal stability, and aging. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. Research speculates that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT5 is a class III sirtuin family member. Several transcript variants exist as the result of alternative splicing.
DescriptionSIRT5 Polyclonal Antibody . Unconjugated. Raised in: Rabbit.
FormulationPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ9NXA8
PurificationAffinity Purified
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 216-310 of human SIRT5 (NP_036373.1)
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.
Alternative NamesSIR2L5
ApplicationWB; Recommended dilution: WB 1:500 - 1:2000