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SIRT2 Polyclonal Antibody


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Western blot - SIRT2 Polyclonal Antibody
Immunofluorescence a- SIRT2 Polyclonal Antibody
Immunohistochemistry - SIRT2 Polyclonal Antibody
Application: IF, IHC, WB
Areas of Research: Histone Acetylation & Deacetylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Rat
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-4702-05050 µl $189.00 
A-4702-100100 µl $299.00 
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Product Overview

SIRT2 (sirtuin homologue 2) is a member of the NAD-dependent histone deacetylase family of proteins (sirtuns) which are involved in a variety of cellular functions. These functions include gene silencing, histone deacetylation, chromosomal stability, and aging. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT2 is a human homolog of the yeast SIR2 and it acts as a transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. This gene's expression rapidly increases during mitosis and is multiply phosphorylated at the G2/M transition of the cell cycle. SIRT2 is part of a phosphorylation cascade where it is phosphorylated late in G2, during M, and into the period of cytokinesis. SIRT2 appears to play an opposing role to SIRT1 in neurodegenerative diseases.

SIRT2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Liquid. BS with 0.02% sodium azide, 50% glycerol, pH7.3.

Human, Rat


Uniprot ID

Affinity Purified

Recombinant Protein of Human SIRT2

Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names

WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:10 - 1:100

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