Epigentek Home
 
EpiGentek Guarantee

SIRT2 Polyclonal Antibody

Share:

Write a Review
Western blot analysis of extracts of various cell lines, using SIRT2 Polyclonal Antibody.
Immunofluorescence analysis of HeLa cell using SIRT2 Polyclonal Antibody. Blue: DAPI for nuclear staining.
Application: IF, IHC, WB
Areas of Research: Histone Acetylation & Deacetylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Rat
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-4702-05050 µl $189.00 
A-4702-100100 µl $299.00 
Availability: Usually Ships in 3-4 Days 
Product Overview

Background
SIRT2 (sirtuin homologue 2) is a member of the NAD-dependent histone deacetylase family of proteins (sirtuns) which are involved in a variety of cellular functions. These functions include gene silencing, histone deacetylation, chromosomal stability, and aging. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT2 is a human homolog of the yeast SIR2 and it acts as a transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. This gene's expression rapidly increases during mitosis and is multiply phosphorylated at the G2/M transition of the cell cycle. SIRT2 is part of a phosphorylation cascade where it is phosphorylated late in G2, during M, and into the period of cytokinesis. SIRT2 appears to play an opposing role to SIRT1 in neurodegenerative diseases.

Description
SIRT2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Specificity
Human, Rat

Isotype
IgG

Uniprot ID
Q8IXJ6

Purification
Affinity Purified

Immunogen
Recombinant Protein of Human SIRT2

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
SIR2, SIR2L, SIR2L2

Application
WB, IHC, IF

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

Epigentek Product Reviews
Epigentek is an epigenetics company that specializes in epigenetic kits, antibodies, reagents, and services for epigenetic research in DNA methylation, histone modification, and chromatin studies. Terms & Conditions | Privacy Policy | Site Map
Copyright © 2017 Epigentek Group Inc. All rights reserved.