BackgroundNonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.
DescriptionSCNN1G Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP51170
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 100-250 of human SCNN1G (NP_001030.2).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesSCNN1G; BESC3; ENaCg; ENaCgamma; PHA1; SCNEG; sodium channel epithelial 1 gamma subunit
ApplicationWB, IHC, IF; Recommended dilution: WB: 1:500-1:2000, IHC: 1:100-1:200, IF:1:50-1:200