BackgroundNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
DescriptionRELA Recombinant Monoclonal Antibody [38F2]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ04206
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human RELA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesTranscription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3), RELA, NFKB3
ApplicationELISA, WB, IF, FC; Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200, FC:1:50-1:200