BackgroundPRMTs (Protein Arginine N-Methyltransferases) can monomethylate or dimethylate arginine residues by transferring methyl groups from S-adenoxylmethionine to the guanidine nitrogen of arginine. PRMT2, also called Protein Arginine N-Methyltransferase 2, methylates arginine residues in proteins, for example histone H4, STAT3, and FBL. With NCOA2, PRMT2 has been shown to act as a coactivator of transactivation mediated by the androgen receptor (AR) and also, with estrogen, PRMT2 has been shown to coactivate estrogen receptor (ER)-mediated transactivation. It may also be implicated in growth regulation processes.
DescriptionPRMT2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP55345
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PRMT2 (NP_996845.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesANM2_HUMAN antibody, EC 2.1.1. antibody, histone arginine N methyltransferase PRMT2 antibody, HMT 1 antibody, HMT1 (hnRNP methyltransferase S. cerevisiae) like 1 antibody, hnRNP methyltransferase like 1 antibody, Hrmt1l1 antibody, MGC111373 antibody, PRMT2 alpha antibody, PRMT2 beta antibody, PRMT2 gamma antibody, PRMT2L2 antibody, Protein arginine methyltransferase 2 antibody, Zf2 antibody
ApplicationWB, IHC, IF; Recommended dilution: WB: 1:500-1:2000, IHC: 1:50-1:200, IF:1:50-1:100
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