BackgroundPrevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).
DescriptionNACA2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9H009
Purification>95%, Protein G purified
ImmunogenRecombinant Human Nascent polypeptide-associated complex subunit alpha-2 protein (1-215AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesNascent polypeptide-associated complex subunit alpha-2, Alpha-NAC-like, Hom s 2.01, Nascent polypeptide-associated complex subunit alpha-like, NAC-alpha-like, NACA2, NACAL
ApplicationELISA, WB; Recommended dilution: WB:1:1000-1:5000