BackgroundEnables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple); endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and interstitial cystitis.
DescriptionMKI67 Recombinant Monoclonal Antibody [16H10]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP46013
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human MKI67
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesProliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67), MKI67
ApplicationELISA, IHC, FC; Recommended dilution: IHC:1:50-1:200, FC:1:50-1:200
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