BackgroundDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Methyl-CpG binding domain protein 2 (MBD2), which can bind to methylated DNA in vivo and in vitro, may serve as a methylation-dependent transcriptional repressor. Also, MBD2 has been demonstrated to be involved in tumorigenesis.
DescriptionMBD2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityMouse, Rat
IsotypeIgG
PurificationAffinity Purified
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 202-411 of human MBD2 (NP_003918.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.
Alternative NamesDemethylase antibody, DMTase antibody, MBD 2 antibody, MBD2_HUMAN antibody, MBD2a antibody, Methyl CpG binding domain protein 2 antibody, Methyl CpG binding protein MBD2 antibody, NY CO 41 antibody
ApplicationWB; Recommended dilution: WB 1:200 - 1:2000